I am depressed with being depressed, fed up with a pessimistic outlook during my waking hours. Even though my situation is grim I am not depressed about that. Even if everything went right my body would still find time and metabolism to be depressed. Although not suicidal I am wretched with the air I breath leaving my body with a scowl as this disease infests every part of your being, those around, those you happen upon, and all the other 'what you need to do' types. It could be described as rotting from within. The chemicals in the body are not correct, or the hormones, so it mucks up everything else causing physical ailments. I have psoriasis on my face and ears, my eyesight has got worse, I keep getting headaches, and abscesses, plus all the aches and pains. I've given up seeing doctors, they have done all they can do, so I keep taking my meds to stop me getting really depressed! I missed one dose of venlafaxine the other week and nearly topped myself, so at least I know they are working in a perverse sort of way.