Depression Forums

General => Medication => Topic started by: Leo on September 11, 2012, 03:55:52 PM

Title: Venlafaxine
Post by: Leo on September 11, 2012, 03:55:52 PM
Hi,

I suffer with Major Depressive Disorder and have done for over 10 years.

I hit a low spell a year ago and was put on Citalopram 10mg. I felt instant relief.
Over the past few months however, my symptoms got worse and I was feeling suicidal and couldn't cope with basic situations. My coping mechanisms were to sleep or cry. I locked myself in the toilets a few times in tears at work.

I am currently signed off work and my doctor has put me on Venlafaxine 75mg. I feel spaced out, have had diarrhea, nausea, anxiety and headaches. I generally feel numb but that is better than feeling suicidal of course!

Do these symptoms pass once you are used to the drug? I've only been on it a week.

Does anyone else have experience with venlafaxine?

I'm still not sure what to do about my work I have been off 2 weeks so far and it has really helped, I have another week left but my doctor has told me just to phone if I need further time off.

Title: Re: Venlafaxine
Post by: Sweetpea on September 11, 2012, 04:33:17 PM
They do say that anti-depressants do usually make you feel worse before feeling better. This is hard. I remember wanting them to work like a pain killer tablet :(.  If things do not improve have a chat with your Dr to put any worries to him/her. S x x x x
Title: Re: Venlafaxine
Post by: Zaf on September 11, 2012, 04:58:23 PM
I've no experience of this drug but agree with shaz xx
Title: Re: Venlafaxine
Post by: Leo on September 12, 2012, 03:41:04 AM
Thankyou for the replies.

Yesterday and today I have bad anxiety - something I never had on Citalopram. I want to go see my doctor but I think they will just tell me the meds take time to work as its only been a week. :s

My line runs out on Tuesday and then I either have to take the holidays I have booked and return to work at the end if that period or get another doctors line.
I am at a lost what to do....and I do think this is helping with the anxiety.
Title: Re: Venlafaxine
Post by: woozywoo on September 12, 2012, 11:15:57 AM
Hi Leo!

I am on venlefaxine 300mg. Have been on it for a few years now and have recently increased it. I can't remember how i felt at the beginning,but i was so low i don't think i cared,cos with or without the tabs i felt awful! They do take a while 2 work as my increase which happened about 2months ago i am only really feeling the benefit now. I know when i increased it made me feel very sick and extremely tired and very spaced out! I say as hard as it is,give it more time

In terms of bein off sick,i have been now for nearly 3months. It started with 2weeks and i was adamant i was goin straight back. Needless 2 say that didn't happen. And chances are i Will be off now until after Christmas. At first i made myself more ill with the worry of bein off. Now i know its what i needed. There mediation and this illness takes time 2 recover from and get well. I think it is extremely hard 2 do this while still working. Every couple of weeks i had the worry about should i go back or should i get another sick note. Now i have made the decision for after Christmas it has been a huge weight lifted off my mind.

Good luck with what you decide! Take care x
Title: Re: Venlafaxine
Post by: Ruth on September 13, 2012, 12:39:36 PM
Hi Leo,
I take venlafaxine. I was on 75mg for 5 months or so and have been on 150mg for about 6 weeks. Honestly I found the first 2 weeks very hard, but my depression was very bad at that point. I was also very anxious about being back on meds having had a bad time with Prozac so a lot of my starting symptoms were not all to do with the tabs. For the first two weeks I had headaches, anxiety, trouble sleeping at night, and drowsy during the day. I was also dizzy, spaced out and had vision problems. My family and psych helped me stick it out and I am glad to say week three was so much better. I still had slightly blurry eyes and was tired during the day but it was so much easier. I need to point out I already have bad eyesight and I sleep a lot because of the depression anyway. By week 4 all I had was tiredness. I noticeed the meds start working a little after 3 days but it took a couple of months before I noticed a stable improvement. My mood was no where near as extreme as it was but I still felt very low so the doc upped my dose. I am now up and about doing things again and I have started to have good days.
Sorry if this is really long. I know this is only my experience and meds effect everyone in different ways. For me trying to stay distracted and not think about my symptoms was helpful in the first two weeks. I slept a lot and watched a lot of tv with my mum. The doc told me to eat a plain meal like cereal 2 prevent feeling sick and this helped a lot. Stevie is right that it can effect your blood pressure so I would get it checked when u go back to the docs, but mine did not seem too worried in the short term.
I hope this was useful. Good luck you will be fine. If you are worried there is no reason not to go back to the docs even for your own peace of mind. They get paid enough after all.
Title: Re: Venlafaxine
Post by: Leo on September 13, 2012, 05:18:31 PM
Thankyou for sharing your experiences.

The nausea and headaches seemed to have eased which is good. I was feeling numb but starting to feel quite low again, and that there isn't much point in getting up.  As daft as it sounds I'm feeling quite anxious about leaving the house now.

I have a meeting with my work tomorrow to 'discuss' my absence but I'm not expecting any support from them. I am but a number in there. The last time I mentioned I had depression to a manager in their it was dismissed.

I spoke with a counsellor on the phone or should I say cried at a counsellor on the phone. I see her on Monday.

Going to persevere with the Venlafaxine, I'm not sure how long you need to be on it before they adjust your dosage.

I already have high blood pressure so the doctors are monitoring it.
Title: Re: Venlafaxine
Post by: Beetzart on September 13, 2012, 05:30:19 PM
Word of advice, try not to miss a dose or stop cold turkey.  I forget to take it yesterday and was very suicidal.
Title: Re: Venlafaxine
Post by: Leo on September 13, 2012, 07:43:50 PM
I will try not to. I missed a dose on Citalopram and felt awful!
Title: Re: Venlafaxine
Post by: Leo on September 29, 2012, 03:02:02 AM
Just thought I would update.

Side effects have subsided, but my sleep is now disturbed again.

I don't feel any huge benefit from the tablets.
 It's hard to judge - I'm not putting myself in stressful situations so don't feel too bad but still hopeless and don't see the point in things.
I was in tears with Occupational Health at our last meeting and basic things like going out for a few hours are exhausting me.
It will be four weeks on Sunday I have been taking the tablets, should I be feeling better?

Title: Re: Venlafaxine
Post by: Sweetpea on September 29, 2012, 08:18:42 AM
We are all different and side effects and benefit from meds vary. I think you should go and see your GP and have a chat about how you are feeling. He may decide to change your meds or advise you to keep on them longer. Take care. S x x x x

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Title: Re: Venlafaxine
Post by: Munchroom on September 29, 2012, 10:26:42 AM
I was on Venlafaxine 300mg (I think) for about a year. Beetzart is right, don't miss a dose or stop them suddenly....  I used to get 'brain zaps' if I left it too long between doses and I had to come off of them very slowly over a few weeks.

They did work though, its just very frustrating that we have to wait so long to see any improvement xx
Title: Re: Venlafaxine
Post by: Leo on September 29, 2012, 01:56:19 PM
Thanks, I have n appointment on Monday with my GP. :)
Title: Re: Venlafaxine
Post by: Leo on October 03, 2012, 03:55:40 AM
Spoke to my GP and she wants me to increase my dose of Venlafaxine.

I'm not sure what to do as I felt a bit better last week so I was given a line for 2 weeks and I have to go back if I want to increase my dose.

I have been given a booklet 'recovery for work'. It's basically about triggers, coping mechanisms etc i am struggling to fill it out as its upsetting me for some reason?

I also called my personnel manager to let her know I was going to be off and she hasn't even bothered to call me back. I am thinking of giving up my team leader position as I expect them to demote me when I go back due to absence anyway. Not to mention, one of the biggest issues is the lack of support and that's not going to change considering individuals who has just been promoted.

I'm not sure even if I can go back...it's such a destructive environment.

Money is getting really tight too!
Title: Re: Venlafaxine
Post by: Sweetpea on October 03, 2012, 09:27:32 AM
Feel for you. Having pressure from work just increases your anxiety. Your Dr seems to be understanding which is a comfort. Take care. S x x x x

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Title: Re: Venlafaxine
Post by: bookletters on October 13, 2012, 01:15:55 PM
Hi Leo,

It took 8 weeks for venlafaxin to work for me, I was convinced it wasn't working at first but I was on it for years and it gave me loads of stability, great drug!
The doc gave me some sleeping tablets until the meds kicked in and that helped as I was not sleeping restfully at all and that was making me very tearful.
Apart from loss of appetite and insomnia I don't recall any major side effects....
Best of luck!!
Title: Re: Venlafaxine
Post by: Leo on October 13, 2012, 07:20:36 PM
Thanks, good to know its worth persevering with.

Just had my dose increased to 150mg and have been given sleeping tablets too. Touch wood no furthers side effects.
Title: Re: Venlafaxine
Post by: bookletters on October 13, 2012, 07:49:49 PM
Yes deffo!
I was convinced it wasn't working at all before the 8 weeks and it kicked in nicely :)
Title: Re: Venlafaxine
Post by: Catbrian on October 13, 2012, 08:10:56 PM
Most AD's are the same, they take time to find the right dose for each individual or to have any noticeable effect.

Hope it goes well
Title: Re: Venlafaxine
Post by: bookletters on October 13, 2012, 08:19:48 PM
I have been on citalopram for 7 months (dose was upped and I had a nasty relapse in july) and I am despairing that it's ever going to get me out of this!!
I feel like I am on a rollercoster: 2 okay days then the rest of the week bad!
Thank God my mood lifts in the evening, I least I have that!!!
Title: Re: Venlafaxine
Post by: Catbrian on October 13, 2012, 10:23:51 PM
My mood improves at night too, most people suffering depression experience similar fluctuations
Title: Re: Venlafaxine
Post by: bookletters on October 13, 2012, 10:55:26 PM
if the new meds haven't been working, could it be that I am slowly getting better "by myself" if that makes sense?
Title: Re: Venlafaxine
Post by: bookletters on October 17, 2012, 04:42:48 PM
Hi Leo,
How are things?
The side effects and symptoms you describe with Venlafaxin I had with citalopram.
Don't hesitate to let your GP up the dose if they think that can help. If doesn't help, don't despair, there are plenty of other drugs out there as not all of them work for everyone. Citalopram was an awful drug for me but it works great for other people....
I am off work too, luckily I am also self employed in addition to my main job so I am earning a little bit of money with my online business. What I like is that I can work at my own pace, at night if needed when my mood is better and it does bring in extra money for when I need to be off work.
I am going to post something about self employment in a different thread now.
Title: Re: Venlafaxine
Post by: Leo on October 17, 2012, 05:25:04 PM
Hi, I don't feel any different to be honest.

Been on the increased dose for 1 week now and no change. In fact I had such a bad day yesterday I stayed in bed all day.

I am looking into part time jobs at the moment. It's not that I don't want to work, just not where I am currently working.
Title: Re: Venlafaxine
Post by: bookletters on October 17, 2012, 08:11:08 PM
Leo, don't hesitate to tell your doc if you feel it's not working for you.
It's always a dilemma as you know it can take some time so you're not sure if it's best to give it up or not.... in any case, you can agree a date by which if it's not working you can switch or something I am sure.
Title: Re: Venlafaxine
Post by: Leo on October 18, 2012, 04:34:52 PM
Yeah, that's a point. I'm so up and down just now. Wednesday I didn't bother getting out of bed, but don't feel too bad today.

I. Think dramatically and permanently reducing my working hours will help in the long run.

Had some council today but I only get another 5 sessions so I don't see us being able to achieve much in those sessions tbh.
Title: Re: Venlafaxine
Post by: bookletters on October 18, 2012, 07:09:17 PM
You'll not feel that you are able to achieve much because the meds aren't helping you properly yet.
Don't hesitate to tell your GP, not all meds work for everyone. I was massively up and down on citalopram, kept thinking "it will kick in eventually".... just it didn't!
Back on venlafaxin now and after two days I am sleeping like a baby, feeling relax and I have a lot more oomph (which is half scaring me as I am thinking is this not too early?? Am I going bipolar??)
Title: Re: Venlafaxine
Post by: Catbrian on October 18, 2012, 09:03:49 PM
It's difficult to know what to do, Leo.  How long have you been on the current AD?  It's easy to get caught in a rut with the same AD doing little for us.  I'd say talk to GP, suggest a change, but sometimes that's never easy either, unless it's a complete cross-over

Good luck
Title: Re: Venlafaxine
Post by: Leo on October 19, 2012, 12:01:12 AM
I was on 75mg for 5 weeks and I have been on the 150mg for 1 week. Should the higher dose have kicked in by now?
Title: Re: Venlafaxine
Post by: bookletters on October 19, 2012, 10:30:45 AM
Not necessarily no Leo, the first time I took venlafaxin, it took 8 weeks. I was sleeping really badly and not knowing what to do with myself.... then at 8 weeks it kicked in nicely!
Give it a bit more time and see your GP if needed :)
Title: Re: Venlafaxine
Post by: Catbrian on October 19, 2012, 08:07:19 PM
I totally agree with Bookletters.  The higher dose maybe doesn't take as long because you were already on it, but it needs to be given a good few weeks.  Although, I'd hope you might start to feel the benefit quite soon.  Those little things might be so subtle that, at first, you don't notice.  For me, it's when I start to spring clean

Leo, you are at a very tough stage in depression.  Sometimes the AD's are our last hope and if they are not materialising as we expect, it's easy to talk ourselves further into a downer.  Give it a little more time, it'll work out.
Title: Re: Venlafaxine
Post by: bookletters on October 27, 2012, 11:01:25 PM
Thinking of you Leo, hope you doing okay xx
Title: Re: Venlafaxine
Post by: willows on October 28, 2012, 03:21:55 PM
I was on 75mg for 2 1/2 weeks and have now been on 150mg for 6 days and are not feeling any benefits yet. Will have to wait and see if venlafaxine is going to work for me because this is my 4th  AD in 8 months.
Title: Re: Venlafaxine
Post by: bookletters on October 28, 2012, 05:48:36 PM
Venlafaxin often works where SRRI's don't Willows. I hope it does the trick for you. From what you have been writing on the forum I personally find you sounding quite a bit better than you were!! xx
Title: Re: Venlafaxine
Post by: Leo on November 06, 2012, 07:36:27 AM
Has anyone experienced involuntary body 'twitches' while being on ADs?

I have noticed this the past week when I'm trying to sleep, my arms and legs tend to twitch. It doesn't bother me, just something I never used to do.
Title: Re: Venlafaxine
Post by: cat69 on November 06, 2012, 09:24:36 AM
Yeah, it's your body relaxing and going into sleep mode!!

My ex used to do it after a night on the booze! used to wake me up! lol

Noticed it too, I'm on venlafaxine... after i knew what it was, it was a nice feeling to know, my body is finally relaxing, and I'll prob nod off soon  =+-
Title: Re: Venlafaxine
Post by: Leo on November 06, 2012, 09:47:34 AM
That's reassuring to know!  =+-
Title: Re: Venlafaxine
Post by: Nay on November 06, 2012, 07:57:42 PM
Yep yep! I get that too Leo x
Title: Re: Venlafaxine
Post by: bookletters on November 06, 2012, 11:15:05 PM
Hope you're feeling better Leo xx
Title: Re: Venlafaxine
Post by: Leo on November 13, 2012, 08:50:21 AM
Does anyone take their Venlafaxine at night?

I'm wondering if this will combat my tiredness throughout the day.
Title: Re: Venlafaxine
Post by: bookletters on November 17, 2012, 04:49:08 PM
Think as you get better your tiredness won't be there so much Leo.
Hope everyone else is doing well xx
Title: Re: Venlafaxine
Post by: Catbrian on November 18, 2012, 07:06:31 PM
Leo, I've always swapped and changed the time I take any meds.  I think if you're feeling groggy in the daytime, take the AD last thing at night.  I always take my meds just as I'm going to bed.

The groggy feeling does subside with time
Title: Re: Venlafaxine
Post by: Leo on November 19, 2012, 01:30:06 AM
Swapped it to night time. Biggest problem is remembering to take the damn thing.

I forgotten take it the other day there and felt no ill effects......perhaps suggests this medication isn't working for me?

However, managing to stay awake some days.

Title: Re: Venlafaxine
Post by: Catbrian on November 20, 2012, 08:10:23 PM
Don't let it fool you, Leo.  If you suddenly stop, after 2-3-4 days, you'd feel like your brain was inside out.